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Abbreviations MNPs: Micro- and Nanoplastics MPs: Microplastics NPs: Nanoplastics PS-NPs: Polystyrene Nanoparticles ROS: Reactive Oxygen Species eNOS: Endothelial Nitric Oxide Synthase NO: Nitric Oxide NAC: N-Acetylcysteine LVOT: Left Ventricular Outflow Tract NLRP3: NOD-, LRR- and Pyrin Domain-containing Protein 3 (inflammasome) NF-B: Nuclear Factor Kappa B Wnt/-catenin: Wingless/Integrated Pathway with -catenin cGAS-STING: Cyclic GMP-AMP Synthase Stimulator of Interferon Genes PAI-1: Plasminogen Activator Inhibitor-1 IIb3: Integrin IIb3 (platelet receptor) PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses References Wright SL, Kelly FJ
Chen B, Dragomir MP, Fabris L, Bayraktar R, Knutsen E, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, Cruz De Los Santos M, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M, Oki E, Fromm B, Ivan C, Bhuvaneshwar K, Gusev Y, Mimori K, Menter D, Sen S, Matsuyama T, Uetake H, Vasilescu C, Kopetz S , Parker-Thornburg J, Taguchi A, Hanash SM, Girnita L, Slaby O, Goel A, Varani G, Gagea M, Li C, Ajani JA, Calin GA
As of February 2026, BPC-157 returned to Category 1 compounding status
